What is Functional Neurological Disorder (FND)

Functional Neurological Disorder (FND) is a neurological condition that affects how the brain and nervous system work. It occurs when brain networks controlling movement, sensation, speech, or awareness stop working properly, even though the structure of the brain is normal. FND is increasingly described as a “brain network disorder”.

FND is one of the most common reasons for referral to a neurologist.

It is estimated to affect at least 50,000–100,000 people in the UK, accounting for around 6% of all neurology outpatient referrals – similar in frequency to conditions such as multiple sclerosis or Parkinson’s disease. Around 8,000 new cases are identified each year in the UK. (Stone et al., Lancet Neurology 2021; NHS England, 2025)

A diagnosis of FND is made by a neurologist, based on positive neurological signs that are specific to the condition, not by exclusion. For example, Hoover’s sign can help confirm functional limb weakness. These positive signs distinguish FND from other neurological disorders and support accurate diagnosis and treatment. NHS England and NICE (NG252, 2025) recognise FND as a neurological disorder of function, reflected in clinical pathways and national service specifications that place FND alongside other neurological conditions within specialised neurology services. Symptoms can include limb weakness or paralysis, functional seizures, walking difficulties, spasms, sensory changes, speech or cognitive problems, and more.

Recovery exists on a spectrum. Some people make significant progress through rehabilitation and support, whilst others focus on managing symptoms and quality of life.

What does functional mean?

In medicine, functional describes a problem in how a part of the body works, rather than damage to its structure. As noted by the Oxford Learner’s Dictionary, a functional disorder is “an illness caused when an organ of the body fails to perform its function”. In FND, this means the nervous system’s function is disrupted. Signals can be misrouted or inhibited, affecting the brain’s control of the body. Modern research using brain imaging and neurophysiological studies shows measurable changes in these networks. FND is therefore understood as a disorder of nervous system function, not a diagnosis of exclusion and not explained by stress or emotion alone.

How FND differs from other neurological conditions

FND can resemble conditions such as Multiple Sclerosis, Parkinson’s disease, or Epilepsy, but the underlying mechanism is different. Those conditions involve structural damage or disease in the nervous system, whereas FND involves abnormal function within normal structure. Both are neurological – they simply differ in how the brain and nervous system are affected.

“Functional Neurological Disorder is often explained to patients as a psychological reaction due to past trauma, or as symptoms due to stress. These explanations often fail, leaving patients feeling alienated, stigmatised, and not believed. The reason for this failure is that these explanations turn a potential risk factor into the cause of the problem.”

— Edwards MJ (2018)

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A diagnosis of FND should be made by a neurologist based on positive neurological signs and specific tests. For example, Hoover’s Sign is a test that can help diagnose limb weakness associated with FND.

Accurate diagnosis is essential to avoid misdiagnosis, as FND can sometimes present alongside other neurological conditions. It’s important to consider that FND may co-exist with other conditions, so comprehensive assessment is crucial.

Throughout history, a lack of understanding of FND has led to people being dismissed, neglected or not believed. To this day this is still happening across the UK, and below are some FND myths sourced from the consensus paper A practical review of functional neurological disorder (FND) for the general physician, written by some of the leading specialists in the field.

The diagnosis of FND should be ‘ruled in’ based on the presence of positive signs.

FND commonly co-occurs with other neurological conditions.

A bizarre presentation does not equate to a diagnosis of FND. Unusual presentations can occur with other neurological conditions.

Shared mechanisms and comorbidities, such as pain and fatigue, may be present between patients with FND. 

FND symptoms are involuntary. Patients are not ‘putting them on’ as have no form of control. Feigning is very rare.

Investigations can be useful to identify comorbid neurological conditions. Other neurological conditions are a strong risk factor for FND.

FND is not misdiagnosed more than other conditions. Erroneously diagnosing FND as another neurological condition can be as harmful as the reverse.

Psychological factors are one of many possible risk factors for FND and should not be considered the sole aetiological cause.

Patients with FND are as disabled, and have as impaired quality of life, as patients with other neurological conditions.

FND treatment is individualised and multidisciplinary, involving combinations of physical and psychological rehabilitation.

Further reading: Lidstone SC, Araújo R, Stone J, Bloem BR. Ten myths about functional neurological disorder. Eur J Neurol. 2020 Nov;27(11):e62-e64. doi: 10.1111/ene.14310. Epub 2020 Jun 4. PMID: 32400011.

Although symptoms of FND are commonly seen in neurology, epilepsy, and paediatric clinics, the exact cause remains unclear. Research suggests that symptoms arise from a problem in how the brain functions – particularly how it processes and sends signals to the body – rather than from structural damage. For some people, FND may follow illness, injury, or psychological stress, but for many, symptoms appear without a clear trigger.

Whilst standard brain scans are often normal, this doesn’t mean nothing is happening. Advanced imaging, such as functional MRI (fMRI), has started to reveal differences in brain network activity in people with FND. These findings reflect the complexity of the brain–body relationship and underscore the need to understand health through a biopsychosocial lens – not just in FND, but across all areas of medicine. As research continues, it’s helping to build a fuller picture of how symptoms develop and how recovery might be supported.

To learn more about Functional Neurological Disorder, we recommend visiting the neurosymptoms website, a key medical resource managed by a leading expert in the field. This site offers valuable insights into understanding FND and is widely used by healthcare professionals.

SYMPTOMS
DIAGNOSIS
TREATMENT

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